Projects granted by the Ministry of Economy and Competitiveness of the Government of Spain, in which Reig Jofre participates:
Project title:USE OF MUCOADHESIVE POLYMERIC FORMULATIONS FOR THE ERADICATION OF HELICOBACTER PYLORI (PYLOMUC)
Reference number:RTC-2017-6643-1
Partners:Laboratorio Reig Jofre S.A.
Bionanoplus S.L.
Universidad de Navarra
Universidad de Sevilla
Funding Agency:Ministry of Science, Innovation and Universities funded this project within the Challenges & Collaboration Subprogram, Call 2017. The project is co-funded by the European Union with the aim of promoting technological development, innovation and quality research.
Objective:The main objective of the project is to develop innovative formulations based on mucoadhesive polymeric systems for the treatment of gastric ulcers caused by Helicobacter pylori infection.
Duration:2018-2021
Project title:TRANSITION TO CLINICAL INVESTIGATION PHASE FOR LICENSE OF THE FIRST VACCINE AGAINST DRUG RESISTANT ACINETOBACTER BAUMANNII (ACINETOCLINIC)
Reference number:RTC-2016- 5161-1
Partners:Vaxdyn
Laboratorio Reig Jofre SA
Draconis Pharma
Instituto de Biomedicina de Sevilla (IBIS)
Hospital Universitario Virgen del Rocío (HUVR)
Centro Tecnológico Leitat
Funding Agency:Ministry of Economy and Competitiveness, co-financed through EU-FEDER funds, within the State Program 2016 Challenges & Colaboration of the State Research Agency, with the main objective of Promoting technological development, innovation and quality research.
Objective:Complete the transition to clinical development in humans (Phase I in healthy volunteers) of the first universal vaccine against infections caused by bacteria resistant to Acinetobacter baumannii antibiotics (VxD-001 vaccine).
Duration:2016-2019
Project title:DEVELOPMENT OF NEW APPROACHES IN THE INDIVIDUALIZED MANAGEMENT OF GYNECOLOGICAL CANCER PATIENTS (PredictGYN)
Reference number:RTC-2015-3821-1
Partners:Ability Pharmaceuticals SL
Althia Health SL
Fundacio Hospital Universitari Vall d’Hebron – Institut de Recerca
Institut de Recerca Biomedica de Lleida
Fundacio Privada Dr. Pifarre
Laboratorio Reig Jofre SA
Oryzon Genomics Diagnostico SL
Funding Agency:Ministry of Economy and Competitiveness, within the State Program of Research, Development and Innovation Oriented to the Challenges of Society under the State Plan of Scientific and Technical Research, and Innovation 2013-2016.
Objective:Identification of molecular markers to develop a prognostic test for patients with endometrial and ovarian cancer. Development of new personalized therapy strategies in endometrial cancer.
Duration:2015-2018
Project title:DEVELOPMENT OF INNOVATIVE FORMULATIONS OF MUCOADHESIVE NANOPARTICLES FOR THE TREATMENT OF MUCOSAL ULCERS (NANOMUC)
Reference number:RTC-2015-4437-1
Partners:Bionanoplus SL
Laboratorio Reig Jofre SA
Universidad de Navarra
Universidad de Sevilla
Funding Agency:Ministry of Economy and Competitiveness, within the State Program of Research, Development and Innovation Oriented to the Challenges of Society under the State Plan of Scientific and Technical Research, and Innovation 2013-2016.
Objective:Development of controlled drug release treatments using innovative formulations of mucoadhesive polymeric nanoparticles. This will allow a longer residence of active principles in the mucous, combining local and systemic action, and resulting in a more effective treatment.
Duration:2015-2017
Project title:CURE4B
Reference number:RTC-2015-4319-1
Partners:Fundacio per a la recerca i la docencia Sant Joan de Deu (FSJD)
Institut Catala d’Oncologia
Laboratorio Reig Jofre SA
Vcn Biosciences SL
Funding Agency:Ministry of Economy and Competitiveness, within the State Program of Research, Development and Innovation Oriented to the Challenges of Society under the State Plan of Scientific and Technical Research, and Innovation 2013-2016.
Objective:Development and validation of oncolytic virus VCN-01 as a clinical candidate for retinoblastoma treatment, the most common type of eye cancer in children.
Duration::2015-2018
Project title:DEVELOPMENT OF HIGH EFFICIENCY SYSTEMS FOR THE PRODUCTION OF BIOSIMILAR ANTIBODIES, ANTI-VEGF (SIMBIO)
Reference number:Expediente: IPT-2012-0663-090000
Partners:Laboratorio Reig Jofre SA
Bioingenium
Centro Tecnologico Leitat
Funding Agency:Ministry of Economy and Competitiveness, National Program of Public-Private Cooperation – INNPACTO subprogram, within the instrumental line of Articulation and Internationalization of the System, under the National Plan for Scientific Research, Development, and Technological Innovation 2008-2011.
Objective:Optimize the production of anti-VEGF biosimilars. Production of the biosimilar of the active principle Ranibizumab, using E coli, and optimization of a eukaryotic cells platform for therapeutic proteins expression.
Duration:2012-2015
Project title:ADENOVIRUS WITHOUT ISOTOPES FOR VACCINATION (ADELVAC)
Reference number:IPT-2012-0551-010000
Partners:VCN Biosciences SL
Laboratorio Reig Jofre SA
ICO
ISC III
Funding Agency:Ministry of Economy and Competitiveness, National Program of Public-Private Cooperation – INNPACTO subprogram, within the instrumental line of Articulation and Internationalization of the System, under the National Plan for Scientific Research, Development, and Technological Innovation 2008-2011.
Objective:Developing a new generation of vaccines based on adenovirus devoid of intrinsic immunogenicity, due to the withdraw of immunodominant epitopes, thus preventing activation of the immune system. New vectors carrying the appropriate antigens may be used for both therapeutic approach of chemoresistant tumors and treatment of infectious diseases.
Duration:2012-2014
Projects in collaboration with scientific societies and research groups:
Project title:Social-health research program for physiological solutions of seawater
Partners:Spanish Society of Outpatient Pediatrics and Primary Care (SEPEAP)
Spanish Society of Allergology and Clinical Immunology (SEAIC)
Spanish Society of Otorhinolaryngology (SEORL)
Laboratorio Reig Jofre SA
Methodology & Objectives:Study on the specialists’ opinion in the use of seawater (presentation and decalogue available only in Spanish):

  • Study with Delphi methodology among 175 specialists in the treatment of upper respiratory tract diseases (50% Paediatrics, 30% Otorhinolaryngology, 20% Allergology).
  • To achieve the highest possible degree of consensus on the effects, use as adjuvant treatment, and clinical experience with nasal washes with seawater.

Survey of seawater users (presentation available only in Spanish):

  • Survey with CATI methodology of 1,350 seawater users as adjuvant treatment of upper respiratory tract diseases (89% congestion, 80% mucus, 70% rhinorrhea).
  • To obtain objective data on the follow-up degree of the medical recommendation on nasal washes with seawater, habits of use, and perception of benefits and overall satisfaction.
Duration:2016-2017
Project title:Transcultural validation in Spanish of the scale HAIR SPECIFIC SKINDEX 29
Partners:Complutense University of Madrid
Hospital 12 de Octubre of Madrid
University of Granada
University of Barcelona
Hospital Clínic of Barcelona
Laboratorio Reig Jofre SA
Objective:Obtaining and cross-cultural validation of the first scale in Spanish capable of measuring the evolution of the quality of life in the female alopecia treatment.
Project presentation at the conference of the Spanish Academy of Dermatology and Venereology (available only in Spanish):

  • Background: Female androgenetic alopecia (FAA) has considerable impact on quality of life. The scale Hair Specific Skindex 29 (HSS29) is the most appropriate for adaptation to Spanish as a tool for following patients in treatment for FAA. This tool assesses disease impact on quality of life over time so that treatments can be tailored to patients’ needs.
  • Conclusions: The psychometric properties of the Spanish version of the HSS29 are similar to those of the original scale and is a useful tool for assessing quality of life in female alopecia.

Paper in the journal of the Spanish Academy of Dermatology Actas Dermo-Sifiliográficas (Abstract in English)
Newsletter ConSalud.es: Impact of alopecia on the women quality of life (available only in Spanish)

Duration:2016-2017