| 1929 | Ramón Reig Jofré created Laboratorio Reig Jofré in the back room of his pharmacy located at Calle Gran de Gracia, in Barcelona.
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| 1958 | He built a new 5-floor production laboratory on Calle Pi i Margall, in Barcelona.
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| 1963 | Agreement with Pierre Fabre to commercialise Ciclotres in Spain, collaborating to consolidate its commercial network in Spain.
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| 1964 | Launch of Vincosedan and Dermo Chabre B6.
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| 1970 | Juan Mª Biosca is appointed as General Manager of Laboratorio Reig Jofré.
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| 1982 | Acquisition of Laboratorio Farmacéutico Vicente Ferrer with its speciality, Oftalmol.
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| 1983 | Specialisation of the equipment in developments in the field of Dermatology.
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| 1989 | Acquisition of Laboratorio Farmacéutico Galepharma Ibérica. Following renovation, the facilities at Sant Adrià del Besós specialise in the production of Penicillin products, and the activity of the Industrial Division as manufacturers for third parties begins.
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| 1992 | Acquisition of the specialities Phonal and Otocerum.
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| 1993 | Acquisition of Laboratorios Medea, specialised in dermatology products such as Complidermol and Medebiotín. The installations are specialised in the production of solid and semi-solid forms.
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| 1995 | Acquisition of Laboratorio Orravan, specialised in the OTC line: Vaseline, Suentillas, Chlorates.
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| 1996 | Acquisition of the product line OTC topical disinfectants from Montplet.
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| 1997 | Acquisition of the Sant Joan Despí/Barcelona plant (SJD) from Boehringer Ingelheim.
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| 1998 | The companies of the Group move to the new headquarters in Sant Joan Despí (Barcelona).
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| 1999 | Acquisition of Laboratorio Ramón Sala with its speciality, Lacteol.
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| 2000 | Acquisition of the GlaxoSmithKline penicillin antibiotic factory in Toledo (Spain).
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| 2000 | Renovation of the Sant Joan Despí plant (RJ Barcelona) to increase the production capacity of the Industrial Services Division. Creation of the International Business Area.
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| 2001 | Specialisation of the plant in Toledo (Spain) (RJ Toledo) in the development of generic products and production of penicillin specialities for third parties around the world.
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| 2002 | Acquisition of package of penicillin antibiotic specialities from Cepa Schwarz with leading brands such as Farmoproina.
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| 2003 | Inauguration of the plant for cephalosporin antibiotic vials for injection, in Toledo (Spain).
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| 2004 | Acquisition of the Madrid Farma Antibiotics actives and the takeover of their commercial network of medical visits, as well as their brands: Ardine, Anaclosil, Pulmictan, Ulcometion and AdineClav.
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| 2006 | Ignasi Biosca Reig, third generation in the family, becomes the CEO of REIG JOFRE Group.
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| 2007 | Creation of Giadic Biotech, joint venture with Oryzon Genomics to carry out research in the field of cancer in women.
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| 2008 | Creation of the Centre of Freeze-drying Excellence in Sant Joan Despí.
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| 2009 | Inauguration of a new sterile freeze-drying plant in Sant Joan Despí (Barcelona).
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| 2009 | Acquisition of Bioglan AB in Malmö (Sweden), specialized in the development and manufacturing of dermatological and topical products.
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